# Resources

Publications, posters, videos, and webinars on spatial biology and liquid biopsy.

## Featured Resources
[Webinar
### Spatial Biomarker Panels for Clinical Trials
Watch Webinar](/resources/spatial-biomarker-panels-for-clinical-trials/)[Publication
### Neoadjuvant botensilimab plus balstilimab response pattern in locally advanced mismatch repair proficient colorectal cancer
Read Publication](/resources/neoadjuvant-botensilimab-plus-balstilimab-response/)[Poster
### Clinical Validation of Circulating Tumor Cell Synaptophysin and Androgen Receptor Expression in Metastatic Prostate Cancer Phenotypes
View Poster](/resources/clinical-validation-ctc-synaptophysin-androgen-receptor/)
## Resource Library

Filters
Clear All Focus Area Liquid Biopsy Spatial Biology Resource Type Article Blog Post Poster Product Documentation Publication Research Spotlight Video Webinar Disease Area Autoimmunity Fetal-Maternal Health Infectious Disease Oncology Transplantation Application Biomarker Development Circulating Tumor Cells Clinical Research Platform CyteFinder Orion
Filters
[Research Spotlight](/resources/spatial-profiling-immune-correlates-mss-crc/) Orion
### Spatial Profiling Uncovers Immune Correlates of Durable Response in Phase 1/2 MSS Colorectal Cancer Trial
[Read Spotlight](/resources/spatial-profiling-immune-correlates-mss-crc/) [Publication](/resources/copanlisib-nivolumab-microsatellite-stable-colorectal/) Orion Nature Communications
### Copanlisib in combination with nivolumab for microsatellite stable colorectal cancer: a phase 1/2 trial
[Read More](/resources/copanlisib-nivolumab-microsatellite-stable-colorectal/) [Publication](https://doi.org/10.1158/2159-8290.CD-26-0171) Orion Cancer Discovery
### Spatial Integration of Protein and Chromosomal States Reveals Early Copy-Number Changes and Genotype-Associated Immune Neighborhoods in Serous Ovarian Cancer Evolution
[View Publication](https://doi.org/10.1158/2159-8290.CD-26-0171) [Publication](https://www.nature.com/articles/s41467-026-74933-w) Orion Nature Communications
### Multiple human transgenes prolong survival of triple-carbohydrate knockout porcine kidney xenografts in nonhuman primates
[View Publication](https://www.nature.com/articles/s41467-026-74933-w) [Video](https://www.youtube.com/watch?v=KOiToZIGN0g) Orion
### Dr. Tanjina Kader on mapping spatial proteomics and chromosomal changes on the same tissue section
[Watch Video](https://www.youtube.com/watch?v=KOiToZIGN0g) [Blog](/resources/multiplex-if-choosing-right-technology/) Orion
### Understanding Multiplex Immunofluorescence: Choosing the Right Technology for Discovery, Biomarker Development, and Clinical Research
[Read Blog](/resources/multiplex-if-choosing-right-technology/) [Poster](https://cdn.indicalab.com/wp-content/uploads/20250923160153/Poster-TLS-Pre-CICON-Workshop-Final.pdf) Orion
### High-Dimensional Characterization of Tertiary Lymphoid Structures Using Orion™, HALO®, and HALO AI
[Download Poster](https://cdn.indicalab.com/wp-content/uploads/20250923160153/Poster-TLS-Pre-CICON-Workshop-Final.pdf) [Blog](/resources/biopharma-high-plex-spatial-proteomics-clinical/) Orion
### Four Ways Biopharma Programs Are Using High-Plex Spatial Proteomics in Clinical Development
[Read Blog](/resources/biopharma-high-plex-spatial-proteomics-clinical/) [Webinar](https://www.youtube.com/watch?v=-TU4dRAxydE) Orion
### Inside Orion™ HT: The High-Throughput Spatial Proteomics Platform Built for Biomarker-Driven Clinical Research
[Watch Webinar](https://www.youtube.com/watch?v=-TU4dRAxydE) [Publication](https://doi.org/10.1200/JCO.2026.44.16_suppl.5041) CyteFinder Journal of Clinical Oncology
### Clinical validation of circulating tumor cell synaptophysin and androgen receptor expression in metastatic prostate cancer phenotypes.
[View Publication](https://doi.org/10.1200/JCO.2026.44.16_suppl.5041) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/691cd6e9b37a23fdd7d358244e8fcbac9fc2738b.pdf)
### Clinical Validation of Circulating Tumor Cell Synaptophysin and Androgen Receptor Expression in Metastatic Prostate Cancer Phenotypes
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/691cd6e9b37a23fdd7d358244e8fcbac9fc2738b.pdf) [Blog](/resources/spatial-proteomics-clinical-research-platform/) Orion
### Spatial Proteomics for Clinical Research: A Platform Perspective
[Read Blog](/resources/spatial-proteomics-clinical-research-platform/) [Video](https://www.youtube.com/watch?v=BBtWzia2sts) Orion
### Dr. Kevin Byrd on identifying the minimal signature needed for clinical trials
[Watch Video](https://www.youtube.com/watch?v=BBtWzia2sts) [Video](https://www.youtube.com/watch?v=_oGC1KRVN2U) CyteFinder
### Dr. Pashtoon Kasi on the impact of circulating tumor cells on clinical research
[Watch Video](https://www.youtube.com/watch?v=_oGC1KRVN2U) [Video](https://www.youtube.com/watch?v=07vUECRJ1Mk) Orion
### Dr. Peter Sorger on How His Team Uses Orion™ for Both Discovery and Clinical Applications
[Watch Video](https://www.youtube.com/watch?v=07vUECRJ1Mk) [Video](https://www.youtube.com/watch?v=2nT5Y7rtM9Q) Orion
### How can spatial proteomics be implemented in clinical research settings?
[Watch Video](https://www.youtube.com/watch?v=2nT5Y7rtM9Q) [Publication](https://doi.org/10.1016/j.immuni.2026.03.003) Orion Immunity
### Distinct tissue niches contribute to prostate tissue-resident memory CD8+ T cell differentiation and heterogeneity
[View Publication](https://doi.org/10.1016/j.immuni.2026.03.003) [Publication](https://doi.org/10.1038/s41587-026-03099-z) CyteFinder Nature Biotechnology
### mRNA vaccine immunity is enhanced by hepatocyte detargeting and not dependent on dendritic cell expression
[View Publication](https://doi.org/10.1038/s41587-026-03099-z) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/c2e2fde8a721b66ae4c301cecadcb22b6800922d.pdf) Orion
### Integrative spatial profiling of protein and chromosomal alterations across normal, precancer, and cancer revealed the presence of aneuploidy in the normal fallopian tube
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/c2e2fde8a721b66ae4c301cecadcb22b6800922d.pdf) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC7618831/) CyteFinder Cancer Immunology Research
### Ex Vivo Immuno-Oncology Platform Reveals Spatial T Cell Infiltration Patterns Linked to ATR Inhibition Responses in High-Grade Serous Ovarian Cancer
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC7618831/) [Webinar](https://rarecyte.com/webinar-spatial-biomarker-panels-for-clinical-trials.html) Orion
### Spatial Biomarker Panels for Clinical Trials
[Watch Webinar](https://rarecyte.com/webinar-spatial-biomarker-panels-for-clinical-trials.html) [Publication](https://doi.org/10.64898/2026.03.09.710650) Orion bioRxiv
### Spatial Landscape of Pregnancy-Associated Triple Negative Breast Cancer and Mammary Gland Involution
[View Publication](https://doi.org/10.64898/2026.03.09.710650) [Publication](https://doi.org/10.1016/j.media.2025.103905) Orion Medical Image Analysis
### Immunocto: a massive immune cell database auto-generated for histopathology
[View Publication](https://doi.org/10.1016/j.media.2025.103905) [Publication](https://doi.org/10.1097/pai.0000000000001311) CyteFinder Applied Immunohistochemistry & Molecular Morphology
### Quantitative Assays for TROP2 Measurement in Breast Cancer and Comparison to H-Score
[View Publication](https://doi.org/10.1097/pai.0000000000001311) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC12881594/) CyteFinder Nature Communications
### Extracellular matrix mediates circulating tumor cell clustering in triple-negative breast cancer metastasis
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC12881594/) [Webinar](https://www.youtube.com/watch?v=9ytbxSNuIKQ) Orion
### Mastering Multiplex Immunofluorescence: Easy Strategies for Reliable Spatial Biology Results
[Watch Webinar](https://www.youtube.com/watch?v=9ytbxSNuIKQ) [Publication](https://doi.org/10.1016/j.ejso.2025.111357) CyteFinder European Journal of Surgical Oncology
### Circulating tumor cells predict relapse in head and neck mucosal squamous cell carcinoma
[View Publication](https://doi.org/10.1016/j.ejso.2025.111357) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC12823403/) Orion Nature Medicine
### Immune profiling in a living human recipient of a gene-edited pig kidney
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC12823403/) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC12805936/) CyteFinder Cancer Research Communications
### Surface Marker Identification to Capture Live Circulating Tumor Cells in Metastatic Triple-Negative Breast Cancer
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC12805936/) [Blog](/resources/orion-multiplex-if-diagnostic-pathology/) Orion
### Orion: The Power of Multiplex IF Imaging in Research Diagnostic Pathology
[Read Blog](/resources/orion-multiplex-if-diagnostic-pathology/) [Webinar](https://www.youtube.com/watch?v=lNY-31npm6M) Orion
### Bridging the Discovery-to-Translational Gap in Spatial Biology
[Watch Webinar](https://www.youtube.com/watch?v=lNY-31npm6M) [Publication](https://doi.org/10.1158/1078-0432.CCR-25-0244) CyteFinder Clinical Cancer Research
### Pre-clinical Modeling of Navtemadlin Pharmacokinetics, Pharmacodynamics, and Efficacy in IDH-wildtype Glioblastoma
[View Publication](https://doi.org/10.1158/1078-0432.CCR-25-0244) [Publication](https://doi.org/10.3390/cancers17162717) CyteFinder Cancers
### Comprehensive Longitudinal Linear Mixed Modelling of CTCs Illuminates the Role of Trop2, EpCAM, and CD45 in CTC Clustering and Metastasis
[View Publication](https://doi.org/10.3390/cancers17162717) [Publication](https://arxiv.org/abs/2508.14681) Orion arXiv
### Virtual Multiplex Staining for Histological Images using a Marker-wise Conditioned Diffusion Model
[View Publication](https://arxiv.org/abs/2508.14681) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC12331977/) Orion Nature Communications
### Integrative multi-omics reveals a regulatory and exhausted T-cell landscape in CLL and identifies galectin-9 as an immunotherapy target
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC12331977/) [Publication](https://arxiv.org/abs/2508.04734) Orion arXiv
### Cross-Domain Image Synthesis: Generating H&E from Multiplex Biomarker Imaging
[View Publication](https://arxiv.org/abs/2508.04734) [Blog](/resources/spatial-proteomic-panel-design-challenges/) Orion
### The 3 Biggest Challenges When Designing a Spatial Proteomic Panel
[Read Blog](/resources/spatial-proteomic-panel-design-challenges/) [Article](https://datascience.cancer.gov/news-events/news/nci-funded-tool-combines-imaging-modalities-aid-pathologists-and-machine-learning) National Cancer Institute
### NCI-Funded Tool Combines Imaging Modalities to Aid Pathologists and Machine Learning (ML)
[Read Article](https://datascience.cancer.gov/news-events/news/nci-funded-tool-combines-imaging-modalities-aid-pathologists-and-machine-learning) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC12213210/) CyteFinder Clinical Cancer Research
### Quantitative Protein Expression of Antibody-Drug Conjugate Targets in EGFR Mutated and Wild-Type Non-Small Cell Lung Cancer
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC12213210/) [Publication](https://doi.org/10.1172/jci.insight.187381) CyteFinder JCI Insight
### Resident memory T cell development is gradual and shows AP-1 gene expression in mature cells
[View Publication](https://doi.org/10.1172/jci.insight.187381) [Publication](https://doi.org/10.1080/07366205.2025.2534299) CyteFinder BioTechniques
### A novel device for buffy coat collection
[View Publication](https://doi.org/10.1080/07366205.2025.2534299) [Blog](/resources/spatial-transcriptomics-to-protein-profiling/) Orion
### The Path to Clinical Relevance: Moving from Spatial Transcriptomics to Protein Profiling
[Read Blog](/resources/spatial-transcriptomics-to-protein-profiling/) [Article](https://www.drugdiscoverynews.com/optimizing-spatial-proteomics-workflows-for-discovery-and-translation-16410) Drug Discovery News
### Optimizing spatial proteomics for discovery and translational research
[Read Article](https://www.drugdiscoverynews.com/optimizing-spatial-proteomics-workflows-for-discovery-and-translation-16410) [Blog](https://www.drugdiscoverynews.com/optimizing-spatial-proteomics-workflows-for-discovery-and-translation-16410) Orion
### Optimizing spatial proteomics for discovery and translational research
[Read Blog](https://www.drugdiscoverynews.com/optimizing-spatial-proteomics-workflows-for-discovery-and-translation-16410) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC12258720/) Orion bioRxiv
### Spatial Biology and Organoid Technologies Reveal a Potential Therapy-Resistant Cancer Stem Cell Population in Pancreatic Ductal Adenocarcinoma
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC12258720/) [Webinar](https://www.youtube.com/watch?v=kXgGKDIMSd8) Orion
### Breaking Barriers in Spatial Proteomics with Single-Round Imaging
[Watch Webinar](https://www.youtube.com/watch?v=kXgGKDIMSd8) [Publication](https://arxiv.org/abs/2505.10294) Orion arXiv
### MIPHEI-ViT: Multiplex Immunofluorescence Prediction from H&E Images using ViT Foundation Models
[View Publication](https://arxiv.org/abs/2505.10294) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC12083604/) CyteFinder medRxiv
### Validation and Prospective Testing of a High Sensitivity, Quantitative Analytic Assay for HER2 on Histopathology Slides
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC12083604/) [Webinar](https://www.drugdiscoverynews.com/exploring-new-frontiers-in-pancreatic-cancer-treatment-with-spatial-biology-16277) Orion
### Exploring New Frontiers in Pancreatic Cancer Treatment with Spatial Biology
[Watch Webinar](https://www.drugdiscoverynews.com/exploring-new-frontiers-in-pancreatic-cancer-treatment-with-spatial-biology-16277) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC12226049/) CyteFinder JCI Insight
### Imlunestrant, a next-generation oral SERD, overcomes ESR1 mutant resistance in estrogen receptor-positive breast cancer
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC12226049/) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/c9e7039c1a1a3fde2a07116c56f403b2b8d825a1.pdf) Orion
### Novel Digital Pathology Algorithms to Explore the Role of Tumor Microenvironment in Next Generation Immuno-oncology Clinical Trials Utilizing 17-plex Fluorescent Immunohistochemistry
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/c9e7039c1a1a3fde2a07116c56f403b2b8d825a1.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/45652abe778b0db13bb49cd20b84dd4b4f851ba4.pdf) Orion
### Phenoplex spatial analysis of whole-slide colon adenocarcinoma imaged with Orion 13-plex one-round staining and imaging
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/45652abe778b0db13bb49cd20b84dd4b4f851ba4.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/43fb6d4a8510166e936d250b3bf172e2f669bfa3.pdf) CyteFinder
### Quantitative analysis of HER2, HER3, and γH2AX expression on circulating tumor cells for pharmacodynamic measurement in clinical trials
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/43fb6d4a8510166e936d250b3bf172e2f669bfa3.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/73a7d9d2e53c138d638b4314a30b15752d6aa4a7.pdf) Orion
### Simultaneous, high-throughput detection of RNA and protein biomarkers using the Orion™ imaging system and HCR™ Gold for comprehensive analysis of tumor samples in clinical trials
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/73a7d9d2e53c138d638b4314a30b15752d6aa4a7.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/292db0843364ffa19d1b2f9a08ce8fc6fd705e65.pdf) CyteFinder
### Accurate, high-throughput spatial profiling of whole slide samples with the Paletrra™ multiplexed image analysis pipeline
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/292db0843364ffa19d1b2f9a08ce8fc6fd705e65.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/246a94d07c9a47c844784f113f57f4415bf84a5c.pdf) CyteFinder
### Development of a CTC Based Assay to Characterize MAOA Expression in Metastatic Prostate Cancer
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/246a94d07c9a47c844784f113f57f4415bf84a5c.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/8530ebc1c8eaaa7c1ca9563abab5872a1edd6193.pdf) Orion
### Enabling scalable, precise, and fast spatial biology studies with Orion and OMERO Plus
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/8530ebc1c8eaaa7c1ca9563abab5872a1edd6193.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/35f46208b170ebd5d8cd8d1d403549997581722a.pdf)
### Characterization of GM-CSF and G-CSF expressing cell subtypes in the tumor microenvironment using the Paletrra™ multiplex immunofluorescence assay integrated with RNAscope™
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/35f46208b170ebd5d8cd8d1d403549997581722a.pdf) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC11985722/) CyteFinder Cellular and Molecular Life Sciences
### Portal venous circulating tumor cells as a biomarker for relapse prediction in resected pancreatic cancer
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC11985722/) [Publication](https://doi.org/10.1038/s41590-025-02119-5) Orion Nature Immunology
### ImmGenMaps, an open-source cartography of the immune system
[View Publication](https://doi.org/10.1038/s41590-025-02119-5) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC11952478/) CyteFinder bioRxiv
### Multiomic analysis identifies suppressive myeloid cell populations in human TB granulomas
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC11952478/) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC12092302/) CyteFinder Nature Medicine
### Neoadjuvant triplet immune checkpoint blockade in newly diagnosed glioblastoma
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC12092302/) [Publication](https://doi.org/10.1101/2025.02.12.637857) CyteFinder bioRxiv
### A pathogenic subpopulation of human glioma associated macrophages linked to glioma progression
[View Publication](https://doi.org/10.1101/2025.02.12.637857) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC11838510/) Orion bioRxiv
### Swirling motion of breast cancer cells radially aligns collagen fibers to enable collective invasion
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC11838510/) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/38181b42312e8912f6bb4f99b8498af06b1b9774.pdf) CyteFinder
### Elevated Levels of Circulating Endothelial Cells in Pregnancies Complicated by Pre-Eclampsia and/or Fetal Growth Restriction
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/38181b42312e8912f6bb4f99b8498af06b1b9774.pdf) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC12130810/) CyteFinder Cancer Discovery
### Multimodal Spatial Profiling Reveals Immune Suppression and Microenvironment Remodeling in Fallopian Tube Precursors to High-Grade Serous Ovarian Carcinoma
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC12130810/) [Publication](https://doi.org/10.1016/j.ccell.2024.11.005) CyteFinder Cancer Cell
### Chemotherapy induces myeloid-driven spatially confined T cell exhaustion in ovarian cancer
[View Publication](https://doi.org/10.1016/j.ccell.2024.11.005) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC11578893/) Orion Nature
### A spatial human thymus cell atlas mapped to a continuous tissue axis
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC11578893/) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC11588665/) Orion Nature Immunology
### Cutaneous T cell lymphoma atlas reveals malignant TH2 cells supported by a B cell-rich tumor microenvironment
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC11588665/) [Article](https://www.biocompare.com/Editorial-Articles/615472-Balancing-Sensitivity-and-Throughput-with-Multiplex-Immunoassays/) Biocompare
### Balancing Sensitivity and Throughput with Multiplex Immunoassays
[Read Article](https://www.biocompare.com/Editorial-Articles/615472-Balancing-Sensitivity-and-Throughput-with-Multiplex-Immunoassays/) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/f6e029d0a3ad855ff644046c0b1c1c20cf771df2.pdf) CyteFinder Orion
### Next Gen Liquid Biopsy: Comprehensive Analysis from a Single Tube of Blood
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/f6e029d0a3ad855ff644046c0b1c1c20cf771df2.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/53da4736fe7d0186e018ddf013f2ef6cb43083b1.pdf) Orion
### Characterizing the tumor microenvironment of a colorectal adenocarcinoma sample with the Orion spatial biology platform and HALO quantitative image analysis
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/53da4736fe7d0186e018ddf013f2ef6cb43083b1.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/4d6bfdd654c94f14375dfcd41aa3494bb7569e4b.pdf) CyteFinder
### Deep phenotyping and spatial interrogation of the NSCLC tumor microenvironment using the fully validated Next Generation MultiOmyx™ Platform
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/4d6bfdd654c94f14375dfcd41aa3494bb7569e4b.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/3ead81c1afe8cf6a2b788e6f26a64279f3abf545.pdf) Orion
### Phenoplex™ spatial analysis of whole-slide colon adenocarcinoma imaged with Orion 13-plex one-round staining and imaging
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/3ead81c1afe8cf6a2b788e6f26a64279f3abf545.pdf) [Webinar](https://vimeo.com/1014288079) Orion
### Accelerating Data and Throughput in Spatial Imaging: A Core Facility Perspective
[Watch Webinar](https://vimeo.com/1014288079) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC11682930/) CyteFinder Cell
### Ovarian cancer-derived IL-4 promotes immunotherapy resistance
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC11682930/) [Article](https://www.nature.com/articles/s43586-024-00330-6) Nature Reviews Methods Primers
### Spatial multiplexing and omics
[Read Article](https://www.nature.com/articles/s43586-024-00330-6) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC11162492/) CyteFinder npj Breast Cancer
### Pure estrogen receptor antagonists potentiate capecitabine activity in ESR1-mutant breast cancer
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC11162492/) [Webinar](https://www.youtube.com/watch?v=vJ3YH4z1YKI) CyteFinder
### New Discoveries in HER2 Detection: A Novel Method of Multimodal Detection of HER2 from a Single Tube of Blood
[Watch Webinar](https://www.youtube.com/watch?v=vJ3YH4z1YKI) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC11018817/) CyteFinder Nature Communications
### Reciprocal antagonism of PIN1-APC/CCDH1 governs mitotic protein stability and cell cycle entry
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC11018817/) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC11108788/) Orion Nature Aging
### Human skeletal muscle aging atlas
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC11108788/) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/bf293dca89c166ae45c117d42bec62d06749f553.pdf) CyteFinder
### Real-time monitoring of CTC number, biomarker expression, and kinetics as prognostic and predictive markers in patients with GI malignancies
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/bf293dca89c166ae45c117d42bec62d06749f553.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/2ec0a38e574f1e6f052748aa3082899213119317.pdf) Orion
### Orion™: 17-plex single-step stain and imaging of normal lung section adjacent to non-small cell lung carcinoma
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/2ec0a38e574f1e6f052748aa3082899213119317.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/c27264afefd6af3ec20ebef325ebfae811dc7adf.pdf) Orion
### Quantitative analysis of colorectal adenocarcinoma images obtained by one step 15-plex staining followed by imaging with the Orion™ spatial biology platform
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/c27264afefd6af3ec20ebef325ebfae811dc7adf.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/360436f6c2d14d82f253816115d89e2ace4233e2.pdf) CyteFinder
### Development and analytic validation of an ARv7 / PSMA dual biomarker circulating tumor cell assay
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/360436f6c2d14d82f253816115d89e2ace4233e2.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/f24e3e19abdbc04fe6d294d046d9639ecd410e6e.pdf) CyteFinder
### Development and validation of an assay for the characterization of SSTR2 expression on CTCs from liquid biopsies
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/f24e3e19abdbc04fe6d294d046d9639ecd410e6e.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/11e01f7eef63bc79d6b7a2eb7ed3d669b7138a8e.pdf) Orion
### Exploring interplay between tumor intrinsic features and immune cell phenotypes in multi-tumor tissue microarrays by a single step 15-plex fluorescence immunohistochemistry and imaging on the Orion Platform
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/11e01f7eef63bc79d6b7a2eb7ed3d669b7138a8e.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/7247dafad9b2e856904b401c6584cc22f7e7c727.pdf) Orion
### Multiplex data utilizing a single-step staining and imaging workflow for the investigation of multiple sample types
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/7247dafad9b2e856904b401c6584cc22f7e7c727.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/1d53c4fd513f070a81185a8ea324959ba0be4a4f.pdf) Orion
### Orion™: 14-plex clinical sample imaging of liver cancer modalities using one-step staining and imaging
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/1d53c4fd513f070a81185a8ea324959ba0be4a4f.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/6096d779abf0b428b91dbd36b5c562f73344a99c.pdf)
### Proof-of-concept study to enumerate large oncosomes using the RareCyte CTC platform
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/6096d779abf0b428b91dbd36b5c562f73344a99c.pdf) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC10982640/) CyteFinder Clinical Cancer Research
### Phase II Study of Eribulin plus Pembrolizumab in Metastatic Soft Tissue Sarcomas: Clinical Outcomes and Biological Correlates
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC10982640/) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/3666634b4df21d0aa7c0264b1d50b6ae93f15ed4.pdf) CyteFinder
### Demonstration of RNA Sequencing of Circulating Trophoblast Cells from Maternal Blood
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/3666634b4df21d0aa7c0264b1d50b6ae93f15ed4.pdf) [Video](https://www.youtube.com/watch?v=x-InH3ky8_4) CyteFinder
### In Utero Program: Detecting and Isolating Circulating Trophoblasts with CyteFinder
[Watch Video](https://www.youtube.com/watch?v=x-InH3ky8_4) [Video](https://www.youtube.com/watch?v=inAMb6HIc0A) Orion
### Exploring interplay between tumor intrinsic features and immune cell phenotypes in multi-tumor tissue microarrays by a single step 15-plex fluorescence immunohistochemistry and imaging on the Orion Platform
[Watch Video](https://www.youtube.com/watch?v=inAMb6HIc0A) [Publication](https://doi.org/10.1002/pd.6529) CyteFinder Prenatal Diagnosis
### Noninvasive single-cell-based prenatal genetic testing: A proof of concept clinical study
[View Publication](https://doi.org/10.1002/pd.6529) [Publication](https://doi.org/10.1002/cncy.22803) CyteFinder Cancer Cytopathology
### Detection of effusion tumor cells under different storage and processing conditions
[View Publication](https://doi.org/10.1002/cncy.22803) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/16a6f80f656d101bdd81726d83d0246d16619b83.pdf) CyteFinder
### A Novel Method for Placental Evaluation: Isolation of Intact Circulating Trophoblast Cells from Maternal Circulation
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/16a6f80f656d101bdd81726d83d0246d16619b83.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/bbbfc64e7abf904c60d82b78a71d022349172b2e.pdf) Orion
### Neoadjuvant botensilimab plus balstilimab (BOT/BAL) in resectable mismatch repair proficient and deficient colorectal cancer: NEST-1 clinical trial
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/bbbfc64e7abf904c60d82b78a71d022349172b2e.pdf) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC10761880/) CyteFinder npj Breast Cancer
### Qualification of a multiplexed tissue imaging assay and detection of novel patterns of HER2 heterogeneity in breast cancer
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC10761880/) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC10782385/) CyteFinder Frontiers in Immunology
### Antigen presentation deficiency, mesenchymal differentiation, and resistance to immunotherapy in the murine syngeneic CT2A tumor model
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC10782385/) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC10693413/) CyteFinder Frontiers in Oncology
### Circulating tumor cell enumeration, biomarker analyses, and kinetics in patients with colorectal cancer and other GI malignancies
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC10693413/) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/e2a4d1d2eba9671c2f2e5c868c979ee21c8756ed.pdf) Orion
### Orion™: 17-plex single-step stain and imaging of colorectal adenocarcinoma
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/e2a4d1d2eba9671c2f2e5c868c979ee21c8756ed.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/7ead5238ea722b6648acd09881ab5ff4b4bf967b.pdf) Orion
### Orion™: 15-plex single-step stain and imaging of tonsil tissue with reactive lymphoid hyperplasia
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/7ead5238ea722b6648acd09881ab5ff4b4bf967b.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/6be2ae5a987208dfe87a20a87e46a5794938aecd.pdf) Orion
### Orion™: 16-plex single-step stain and imaging of oral squamous cell carcinoma
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/6be2ae5a987208dfe87a20a87e46a5794938aecd.pdf) [Webinar](https://www.youtube.com/watch?v=XZj-1MYLvdU) Orion
### Use of Open-Source Software for Quantitative Analysis of Multiplex Images
[Watch Webinar](https://www.youtube.com/watch?v=XZj-1MYLvdU) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC11863877/) CyteFinder The Journal of Liquid Biopsy
### Liquid biopsy kinetics and detection of ERBB2 amplification/HER2-positivity in refractory hepatocellular carcinoma
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC11863877/) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC10611560/) Orion Oncogene
### Neoadjuvant botensilimab plus balstilimab response pattern in locally advanced mismatch repair proficient colorectal cancer
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC10611560/) [Article](https://hms.harvard.edu/news/new-tool-diagnosing-cancer) Harvard Medical School
### A New Tool for Diagnosing Cancer: Platform combines structural details with molecular information about a tumor
[Read Article](https://hms.harvard.edu/news/new-tool-diagnosing-cancer) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC10368530/) Orion Nature Cancer
### High-plex immunofluorescence imaging and traditional histology of the same tissue section for discovering image-based biomarkers
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC10368530/) [Article](https://newsroom.uw.edu/postscript/new-test-might-expand-ability-find-tumor-cells-blood) University of Washington
### New test might expand ability to find tumor cells in blood
[Read Article](https://newsroom.uw.edu/postscript/new-test-might-expand-ability-find-tumor-cells-blood) [Webinar](https://www.youtube.com/watch?v=9LUkgLMCtTw) Orion
### Multimodal Tissue Imaging and Machine Learning to Advance Precision Medicine
[Watch Webinar](https://www.youtube.com/watch?v=9LUkgLMCtTw) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/b4fe65d132e5579cb5e0a30c9bee5d7ff7f632ab.pdf) CyteFinder
### Novel method for the detection and evaluation of disease biomarkers on white blood cells from liquid biopsies
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/b4fe65d132e5579cb5e0a30c9bee5d7ff7f632ab.pdf) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC10083432/) CyteFinder Frontiers in Oncology
### Accurate isolation and detection of circulating tumor cells using enrichment-free multiparametric high resolution imaging
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC10083432/) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC10013750/) CyteFinder PNAS
### Metastasis from the tumor interior and necrotic core formation are regulated by breast cancer-derived angiopoietin-like 7
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC10013750/) [Video](https://www.youtube.com/watch?v=hlVGE7xT3l0) CyteFinder
### Precision Medicine vs Persuasion Medicine: Measuring vs Reading HER2
[Watch Video](https://www.youtube.com/watch?v=hlVGE7xT3l0) [Article](https://www.selectscience.net/editorial-articles/quantitative-microscopy-for-precision-spatial-biology-from-samples-to?artID=59982) SelectScience
### Quantitative microscopy for precision spatial biology: “From samples to knowledge”
[Read Article](https://www.selectscience.net/editorial-articles/quantitative-microscopy-for-precision-spatial-biology-from-samples-to?artID=59982) [Webinar](https://bit.ly/3wyTMNk) Orion
### Spatial Analysis and High-Plex Immunofluorescence to Study Human Pancreata in Type 1 Diabetes
[Watch Webinar](https://bit.ly/3wyTMNk) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC10019067/) CyteFinder Cell
### Multiplexed 3D atlas of state transitions and immune interaction in colorectal cancer
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC10019067/) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/d1b5a534d2ceaffe63199065f691671d5a35ae27.pdf)
### Circulating Tumor Cells (CTCs) as liquid biopsies in patients with metastatic colorectal cancer versus other GI malignancies
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/d1b5a534d2ceaffe63199065f691671d5a35ae27.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/2bc44f35b77fd43b4bd27f2041cb7aabce4c2399.pdf) Orion
### Multi-modal digital pathology for colorectal cancer diagnosis by high-plex immunofluorescence imaging and traditional histology of the same tissue section
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/2bc44f35b77fd43b4bd27f2041cb7aabce4c2399.pdf) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC9167783/) CyteFinder Cancer Discovery
### The Spatial Landscape of Progression and Immunoediting in Primary Melanoma at Single-Cell Resolution
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC9167783/) [Publication](https://doi.org/10.1093/ajcp/aqac040) CyteFinder American Journal of Clinical Pathology
### Clinical Validation of a Circulating Tumor Cell Assay Using Density Centrifugation and Automated Immunofluorescence Microscopy
[View Publication](https://doi.org/10.1093/ajcp/aqac040) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC9090706/) CyteFinder Breast Cancer Research and Treatment
### Circulating tumor cell detection: a prospective comparison between CellSearch and Rarecyte platforms in patients with progressive metastatic breast cancer
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC9090706/) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/47664bc4ea5396c04f2ff3ed2b0a11cb471163ca.pdf) CyteFinder
### Molecular Subtyping of Circulating Tumor Cells in Patients with Small Cell Lung Cancer
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/47664bc4ea5396c04f2ff3ed2b0a11cb471163ca.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/e35dfc002f133eaedcf9005374c5ce828f4dc193.pdf) CyteFinder
### Validation of increased sample stability using the AccuCyte®-CyteFinder® CTC Platform to improve logistics in global clinical trials
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/e35dfc002f133eaedcf9005374c5ce828f4dc193.pdf) [Webinar](https://www.youtube.com/watch?v=wYfAwp-hqc0) Orion
### Spatial Biology: Applying Cellular Phenotyping in Health and Disease
[Watch Webinar](https://www.youtube.com/watch?v=wYfAwp-hqc0) [Publication](https://doi.org/10.3390/ijms23052571) CyteFinder International Journal of Molecular Sciences
### Non-Invasive Profiling of Advanced Prostate Cancer via Multi-Parametric Liquid Biopsy and Radiomic Analysis
[View Publication](https://doi.org/10.3390/ijms23052571) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC8837628/) CyteFinder Nature Communications
### Single-cell tumor-immune microenvironment of BRCA1/2 mutated high-grade serous ovarian cancer
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC8837628/) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC8928994/) CyteFinder Current Issues in Molecular Biology
### Single Circulating-Tumor-Cell-Targeted Sequencing to Identify Somatic Variants in Liquid Biopsies in Non-Small-Cell Lung Cancer Patients
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC8928994/) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/1b36e1627f9165fb88b098599dd9f30461c76b80.pdf) Orion
### Qualitative and quantitative evaluation of the tissue micro-environment by high-resolution 17-plex immunofluorescence reveals distinct cell populations
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/1b36e1627f9165fb88b098599dd9f30461c76b80.pdf) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC8508335/) CyteFinder Cancers
### Heterogeneity of Circulating Tumor Cell Neoplastic Subpopulations Outlined by Single-Cell Transcriptomics
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC8508335/) [Publication](https://doi.org/10.1002/cncy.22483) CyteFinder Cancer Cytopathology
### Identification and Characterization of Effusion Tumor Cells (ETCs) From Remnant Pleural Effusion Specimens
[View Publication](https://doi.org/10.1002/cncy.22483) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC8474080/) CyteFinder Nature Medicine
### Evolution of delayed resistance to immunotherapy in a melanoma responder
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC8474080/) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC7925378/) CyteFinder Molecular Cancer Research
### N-Acetyl-L-cysteine Promotes Ex Vivo Growth and Expansion of Single Circulating Tumor Cells by Mitigating Cellular Stress Responses
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC7925378/) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC7956056/) CyteFinder Clinical Cancer Research
### HAND1 and BARX1 Act as Transcriptional and Anatomic Determinants of Malignancy in Gastrointestinal Stromal Tumor
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC7956056/) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/aba45dd3b39b0f74251052cdecc4e0c46bb59efa.pdf) Orion
### The Orion™ platform from RareCyte® enables same-day 21-plex fluorescence tissue analysis
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/aba45dd3b39b0f74251052cdecc4e0c46bb59efa.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/51dd5a4aee911d671443d768abcfc0b4f83899e8.pdf) CyteFinder
### Validation of a dual-marker ARv7/SYP assay for CTC characterization
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/51dd5a4aee911d671443d768abcfc0b4f83899e8.pdf) [Publication](https://doi.org/10.1126/science.abc4776) CyteFinder Science
### SARS-CoV-2 infection protects against rechallenge in rhesus macaques
[View Publication](https://doi.org/10.1126/science.abc4776) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC7723336/) CyteFinder Nature Medicine
### A single-cell landscape of high-grade serous ovarian cancer
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC7723336/) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/58aadb3c678bb5f5f6c7a2552c0c65836fce9f48.pdf) CyteFinder
### Comparison of Circulating Tumor Cell Derived DNA and Circulating Cell-Free DNA from Simultaneous Blood Sampling of Patients with Metastatic Breast Cancer
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/58aadb3c678bb5f5f6c7a2552c0c65836fce9f48.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/cfaa4c07190add36b82fda74e9eb41511f363aa3.pdf) CyteFinder
### Introduction of a robust workflow for the whole-slide acquisition and co-registration of multiplex immunofluorescence tissue images for analysis of a 9-color, 8-marker immunophenotyping assay
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/cfaa4c07190add36b82fda74e9eb41511f363aa3.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/600f37993438d761629a40034f7702ebe3e46ee3.pdf) CyteFinder
### Investigation of custom biomarkers on circulating tumor cells from clinical samples using RarePlex Developer Kits
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/600f37993438d761629a40034f7702ebe3e46ee3.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/bdb0826b695fd28362b87aba2f6918fa7f25becf.pdf) CyteFinder
### Sequential same slide multiplex immunofluorescence and H&E staining for combined phenotypic and morphologic characterization of formalin-fixed paraffin-embedded tissue sections
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/bdb0826b695fd28362b87aba2f6918fa7f25becf.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/558dd9bd9ab2fa4c95bbc225309f5026bd3b7094.pdf) CyteFinder
### Analytic validation of an assay to detect androgen receptor splice variant ARv7 protein expression on circulating tumor cells from prostate cancer patients
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/558dd9bd9ab2fa4c95bbc225309f5026bd3b7094.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/620b26e37450b92a8ce64be315bb8bdce204e7bd.pdf) CyteFinder
### A direct amplicon-based targeted sequencing assay for mutation analysis of single circulating tumor cells and correlation with circulating tumor DNA
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/620b26e37450b92a8ce64be315bb8bdce204e7bd.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/df9f273e4975c9f636d87ec3ab5d23e6348a8093.pdf) CyteFinder
### A multiparameter assay for HER2 protein detection on circulating tumor cells in non-small cell lung cancer
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/df9f273e4975c9f636d87ec3ab5d23e6348a8093.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/0703a5f56b5f99caf544a03bb704d9bf27d6e3ac.pdf)
### Non-invasive profiling of advanced prostate cancer via multi-parametric liquid biopsy and radiomics
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/0703a5f56b5f99caf544a03bb704d9bf27d6e3ac.pdf) [Video](https://www.youtube.com/watch?v=QK_GBhUGG6U) CyteFinder
### Tissue Transcriptomics with CyteFinder® II Instruments
[Watch Video](https://www.youtube.com/watch?v=QK_GBhUGG6U) [Video](https://www.youtube.com/watch?v=cRuF2NWt7i4) CyteFinder
### Working with the RarePlex® Developer Kit
[Watch Video](https://www.youtube.com/watch?v=cRuF2NWt7i4) [Video](https://www.youtube.com/watch?v=A0dhlNEaohs) CyteFinder
### RarePlex Assays: Design and Analytical Validation
[Watch Video](https://www.youtube.com/watch?v=A0dhlNEaohs) [Video](https://www.youtube.com/watch?v=0mR20SxCGI4) CyteFinder
### RarePlex Panel and Developer Assays for CTC Enumeration and Characterization
[Watch Video](https://www.youtube.com/watch?v=0mR20SxCGI4) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/d6eac85be7627ae4445c6583acad89fea879177d.pdf) CyteFinder
### Validation of an assay to detect programmed death-ligand 1 (PD-L1) expression on circulating tumor cells
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/d6eac85be7627ae4445c6583acad89fea879177d.pdf) [Video](https://www.youtube.com/watch?v=OGRzfR8WJfI) Orion
### RareCyte Technology Presentation at Harvard Medical School
[Watch Video](https://www.youtube.com/watch?v=OGRzfR8WJfI) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC6877641/) CyteFinder Scientific Reports
### PIC&RUN: An integrated assay for the detection and retrieval of single viable circulating tumor cells
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC6877641/) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/f726f0de10760766269f5ee61007a03eb5ca6b28.pdf) CyteFinder
### Amplicon-based targeted sequencing of single circulating tumor cells
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/f726f0de10760766269f5ee61007a03eb5ca6b28.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/46ccee5156e1beb1951d23261d9a821d2af165c1.pdf) CyteFinder
### Multiplex Immunofluorescence Staining, Whole Slide Imaging, and Spatial Phenotyping of T cell Exhaustion, Regulatory T cells, and Myeloid Derived Suppressor Cells in Tumor FFPE Samples
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/46ccee5156e1beb1951d23261d9a821d2af165c1.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/9c2a61a02e4d30eac944a8f8a0d21827cd326a4b.pdf) CyteFinder
### Pick-Seq®: Spatial tissue analysis via multi-parameter imaging and RNA sequencing of micro-regions
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/9c2a61a02e4d30eac944a8f8a0d21827cd326a4b.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/5962be5f1b2b288f2c069f7bd7b54890839f426a.pdf) CyteFinder
### Custom biomarker investigation of circulating tumor cells using RarePlex® Developer Kits
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/5962be5f1b2b288f2c069f7bd7b54890839f426a.pdf) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC6959005/) CyteFinder Nature Protocols
### Qualifying antibodies for image-based immune profiling and multiplexed tissue imaging
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC6959005/) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC6702343/) CyteFinder Scientific Reports
### A Rapid Method for Label-Free Enrichment of Rare Trophoblast Cells from Cervical Samples
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC6702343/) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/7718224c0751c60b3df33fbdaca44e3b5da22e33.pdf)
### Sensitive Detection and Quantification of CAR-T Cells in Treated Patients
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/7718224c0751c60b3df33fbdaca44e3b5da22e33.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/d53952701d68ce95a558c1b2cbd6591dcf69613f.pdf) CyteFinder
### Targeted single cell DNA sequencing without prior whole genome amplification for mutational analysis of circulating tumor cells
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/d53952701d68ce95a558c1b2cbd6591dcf69613f.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/7f7d4a637c665a4538d23c001d9b544eb86500de.pdf) CyteFinder
### TCR sequencing from tissue micro-regions and single cells utilizing RareCyte® CytePicker® and Archer® Immunoverse™ technologies
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/7f7d4a637c665a4538d23c001d9b544eb86500de.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/53bc2b36e320e623b1eb748839e276b7353f9da5.pdf) CyteFinder
### Identification, retrieval, and RNA sequencing of single rare antigen-specific T cells from circulation using the RareCyte® platform
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/53bc2b36e320e623b1eb748839e276b7353f9da5.pdf) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC6419430/) CyteFinder BMC Cancer
### Circulating tumor cell investigation in breast cancer patient-derived xenograft models by automated immunofluorescence staining, image acquisition, and single cell retrieval and analysis
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC6419430/) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/65825a0bd90d478bc9af53f3a0ec883e93f349d8.pdf) CyteFinder
### Multiparameter tissue section imaging and retrieval of image-defined micro-regions for RNA sequencing using the RareCyte platform
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/65825a0bd90d478bc9af53f3a0ec883e93f349d8.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/48201173fbd10e458ff4b6cd247bb76336ad47e9.pdf) CyteFinder
### Single cell molecular characterization and PD-L1 expression analysis of model CTC using the RareCyte platform
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/48201173fbd10e458ff4b6cd247bb76336ad47e9.pdf) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC6587831/) CyteFinder Prenatal Diagnosis
### Reliable detection of subchromosomal deletions and duplications using cell-based noninvasive prenatal testing
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC6587831/) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC6410377/) CyteFinder Cell
### A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC6410377/) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/886b7272733f331d2bd933c9cfa2bb97ce0e9542.pdf) CyteFinder
### Novel multi-parameter assays for investigational phenotyping of circulating tumor cells
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/886b7272733f331d2bd933c9cfa2bb97ce0e9542.pdf) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC6075866/) CyteFinder eLife
### Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC6075866/) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/257e56c91de4f4e70aad955abebf6608cf38256c.pdf) CyteFinder
### Detection and retrieval of multiple myeloma cells with single cell molecular confirmation from peripheral blood by multi-parameter immunofluorescence, automated scanning and image analysis
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/257e56c91de4f4e70aad955abebf6608cf38256c.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/b23c054f8b9844ff2c4ff6620e043bfe8684dd65.pdf) CyteFinder
### Development of a multi-parameter immunofluorescence assay for identification of circulating tumor cells with epithelial-mesenchymal phenotype
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/b23c054f8b9844ff2c4ff6620e043bfe8684dd65.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/bf89a48852cf786fd5dfa86cfa70adfc87f16727.pdf) CyteFinder
### Development of a multi-parameter immunofluorescence assay for simultaneous detection of androgen receptor and androgen receptor variant 7 in prostate cancer circulating tumor cells
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/bf89a48852cf786fd5dfa86cfa70adfc87f16727.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/c356efa4eee44bc2226f424d8c5993a26ef893e9.pdf) CyteFinder
### Increased phenotypic depth for automated visual identification of biomarkers on circulating tumor cells by cocktailing epithelial markers EpCAM and cytokeratin
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/c356efa4eee44bc2226f424d8c5993a26ef893e9.pdf) [Poster](https://cdn.sanity.io/files/s3p6uqps/production/5ee59a52aebd07afa411ffafb41049a4f8919b3a.pdf) CyteFinder
### Simultaneous assessment of PD-L1 and IRF1 expression on breast cancer circulating tumor cells
[Download Poster](https://cdn.sanity.io/files/s3p6uqps/production/5ee59a52aebd07afa411ffafb41049a4f8919b3a.pdf) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC5964005/) CyteFinder The Journal of Urology
### Prostate Cancer Disseminated Tumor Cells are Rarely Detected in the Bone Marrow of Localized Patients Undergoing Radical Prostatectomy Across Multiple Rare Cell Detection Platforms
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC5964005/) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC5129580/) CyteFinder Prenatal Diagnosis
### Evidence for feasibility of fetal trophoblastic cell-based noninvasive prenatal testing
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC5129580/) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC4970582/) CyteFinder Journal of the National Comprehensive Cancer Network
### A Distributed Network for Intensive Longitudinal Monitoring in Metastatic Triple-Negative Breast Cancer
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC4970582/) [Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC4430903/) CyteFinder BMC Cancer
### High-recovery visual identification and single-cell retrieval of circulating tumor cells for genomic analysis using a dual-technology platform integrated with automated immunofluorescence staining
[View Publication](https://pmc.ncbi.nlm.nih.gov/articles/PMC4430903/) [Spec Sheet](https://go.pardot.com/l/455452/2019-11-18/7mzyyz/455452/220141/TS20_103.pdf) CyteFinder
### CyteFinder II HT
[View Spec Sheet](https://go.pardot.com/l/455452/2019-11-18/7mzyyz/455452/220141/TS20_103.pdf) [Spec Sheet](https://go.pardot.com/l/455452/2019-11-18/7mzyz2/455452/220143/TS20_104.pdf) CyteFinder
### CyteFinder II
[View Spec Sheet](https://go.pardot.com/l/455452/2019-11-18/7mzyz2/455452/220143/TS20_104.pdf) [Spec Sheet](https://pardot.rarecyte.com/l/455452/2026-02-24/965v3w/455452/1771949067AeuR6syb/Orion_HT_spec_sheet.pdf) Orion
### Orion HT
[View Spec Sheet](https://pardot.rarecyte.com/l/455452/2026-02-24/965v3w/455452/1771949067AeuR6syb/Orion_HT_spec_sheet.pdf) [Spec Sheet](https://pardot.rarecyte.com/l/455452/2025-10-31/961nyb/455452/1761933957WEJWJyeN/2025.07.14___SS___Orion__LE_.pdf) Orion
### Orion LE
[View Spec Sheet](https://pardot.rarecyte.com/l/455452/2025-10-31/961nyb/455452/1761933957WEJWJyeN/2025.07.14___SS___Orion__LE_.pdf) [Spec Sheet](https://go.pardot.com/l/455452/2020-07-15/8p742r/455452/1607104572nfrlJouR/DF_24_101_201203_Orion_Datafile.pdf) Orion
### Orion
[View Spec Sheet](https://go.pardot.com/l/455452/2020-07-15/8p742r/455452/1607104572nfrlJouR/DF_24_101_201203_Orion_Datafile.pdf) [Brochure](https://go.pardot.com/l/455452/2020-07-15/8p7453/455452/1606951069teslfZQe/BR21_101_Orion_Brochure_201202.pdf) Orion
### Orion Spatial Proteomics Platform
[View Brochure](https://go.pardot.com/l/455452/2020-07-15/8p7453/455452/1606951069teslfZQe/BR21_101_Orion_Brochure_201202.pdf) [Article](https://www.selectscience.net/article/advanced-spatial-biology-sheds-new-light-on-therapeutic-research) Orion SelectScience
### Advanced spatial biology sheds new light on therapeutic research
[Read Article](https://www.selectscience.net/article/advanced-spatial-biology-sheds-new-light-on-therapeutic-research) [Article](https://www.selectscience.net/editorial-articles/bringing-spatial-biology-to-the-clinic-a-new-lens-on-cancer-biology/?&artID=58147) Orion SelectScience
### Bringing spatial biology to the clinic: “A new lens on cancer biology”
[Read Article](https://www.selectscience.net/editorial-articles/bringing-spatial-biology-to-the-clinic-a-new-lens-on-cancer-biology/?&artID=58147) [Article](https://www.selectscience.net/article/how-to-unlock-the-complexity-of-tumor-microenvironments) Orion SelectScience
### How to unlock the complexity of tumor microenvironments
[Read Article](https://www.selectscience.net/article/how-to-unlock-the-complexity-of-tumor-microenvironments) [Article](https://www.selectscience.net/product-news/measuring-versus-reading-transforming-the-field-of-quantitative-pathology?artid=58733) CyteFinder SelectScience
### Measuring versus reading – transforming the field of quantitative pathology
[Read Article](https://www.selectscience.net/product-news/measuring-versus-reading-transforming-the-field-of-quantitative-pathology?artid=58733)
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