Exploring interplay between tumor intrinsic features and immune cell phenotypes in multi-tumor tissue microarrays by a single step 15-plex fluorescence immunohistochemistry and imaging on the Orion Platform

How a single-step 15-plex imaging workflow on the RareCyte Orion™ platform is used to explore the interplay between tumor-intrinsic features and immune-cell phenotypes across multi-tumor tissue microarrays.

This video poster from Navigate Biopharma, presented as part of Wellcome Leap, describes a single-step 15-plex fluorescence immunohistochemistry and imaging workflow carried out on the RareCyte Orion™ platform. In a single step, the workflow stains and images a set of fifteen markers.

With that workflow, the study explores the interplay between tumor-intrinsic features and immune-cell phenotypes across multi-tumor tissue microarrays — arrays that place many different tumors together on a single slide so they can be examined side by side.